Protein kinase C in heart failure: a therapeutic target?
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Protein kinase C in heart failure: a therapeutic target?
Heart failure (HF) afflicts about 5 million people and causes 300,000 deaths a year in the United States alone. An integral part of the pathogenesis of HF is cardiac remodelling, and the signalling events that regulate it are a subject of intense research. Cardiac remodelling is the sum of responses of the heart to causes of HF, such as ischaemia, myocardial infarction, volume and pressure over...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2008
ISSN: 0008-6363
DOI: 10.1093/cvr/cvp001